Coronary artery disease happens when fatty deposits called plaque (say "plak") build up inside your coronary arteries. Those are the blood vessels that supply blood and oxygen to your heart muscle. Plaque buildup may reduce the amount of blood that gets to your heart.

Coronary artery disease can cause angina symptoms, such as chest pain or pressure. It can lead to a heart attack. Treatment for coronary artery disease can help relieve symptoms and lower your risk of a heart attack.